Identification of components of the N signal transduction pathway using the yeast two-hybrid system

(Hailing Jin and Amy deHart, University of California, Berkeley)
Gene-for-gene resistance has been found to protect plants against different types of pathogens including bacteria, fungi, nematodes, and viruses. In the past few years, many R genes have been cloned from different plant species, which confer resistance to many types of pathogen. The dominant N gene from tobacco, cloned by transposon tagging, confers resistance to tobacco mosaic virus (TMV) in both tobacco and tomato.